AN UNBIASED VIEW OF CONOLIDINE

These outcomes, together with a earlier report exhibiting that a small-molecule ACKR3 agonist CCX771 reveals anxiolytic-like conduct in mice,two assist the strategy of focusing on ACKR3 as a novel method to modulate the opioid technique, which could open new therapeutic avenues for opioid-similar Conditions.Importantly, these receptors have been lo